Evaluation of Some Immunoregulatory Cytokines in Serum of Rats Exposed to Cadmium and Ethanol
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چکیده
The aim of the present study was to investigate the effects of cadmium (Cd) (5 and 50 mg Cd/l in drinking water) and ethyl alcohol (ethanol, EtOH) (5 g EtOH/kg b.wt., intragastrically), administered alone or simultaneously, on the concentrations of pro-inflammatory (interleukin-1, IL-1α; interleukin-6, IL-6; tumor necrosis factor-α, TNFα and interferon γ, INFγ) and anti-inflammatory (interleukin-4, IL-4) cytokines in the serum of rats. In order to estimate the involvement of Cdor/and EtOH-induced oxidative stress in damage to cytokines, the concentration of protein carbonyl groups (PC), as a marker of oxidative protein damage, was
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تاریخ انتشار 2011